Penicillin
Blended Scotch, honey-ginger syrup and lemon, topped with a peaty Islay float — smoky, spiced and citrus-sharp.
- Difficulty
- advanced
- Prep time
- 6 min
- Strength
- 22.8% ABV
- Glassware
- Rocks glass
- Base
- whisky
- Serves
- 1
Ingredients
- Blended Scotch whisky50ml
- Fresh lemon juice20ml
- Honey syrup15ml
- Ginger syrup10ml
Fresh ginger syrup gives the best heat; not on the standard pantry list, but essential to this drink
- Islay Scotch whisky8ml
Floated on top after straining, not shaken in
Garnish: Candied ginger, Lemon peel
Method
- Add the blended Scotch, lemon juice, honey syrup and ginger syrup to a shaker with ice.
- Shake hard for around 12 seconds.
- Strain into a rocks glass over fresh ice.
- Float the Islay Scotch on top by pouring it slowly over the back of a bar spoon.
- Garnish with candied ginger and a lemon peel.
Equipment
Don't have everything? Here's what works instead.
Cocktail shaker
Household swap: A secure jar or bottle with a tight-fitting lid, shaken firmly.
Hawthorne strainer
Household swap: A slotted kitchen spoon held across the shaker opening.
Missing an ingredient?
Each swap below says what it changes and how to correct for it, so you can decide whether you are making this drink or a neighbouring one.
Instead of Islay Scotch
Best substitute: Blended Scotch
This is the modifier in this drink.
Flavour impact: Loses the smoky top note entirely; the drink becomes a straightforward honey-ginger whisky sour.
What changes
Expect less bitterness and less intensity. Still a good drink, and a slightly different one.
- Bitterness ↓
- Losing bitterness makes the drink rounder and more approachable, and takes away the structure that stopped it tasting like squash.
- Intensity ↓
- A milder ingredient gets buried by whatever else is in the glass, and the drink loses the thing it was named for.
- Character
- you lose smoky, peaty, briny and intense, and you gain honeyed, smooth, light smoke and balanced. Numbers can't see this: two ingredients can be identically sour and still smell nothing alike.
To correct for it
- A dash of bitters restores some of the backbone without changing anything else.
- Increase the measure, or accept a gentler drink and reduce the components competing with it.
Moderate confidenceWorkable as a drink, but changes the character the recipe is built around.Shifts the drink
Make it better
- A little Islay Scotch goes a long way for the float — 8ml is usually plenty of smoke.
- Make your own ginger syrup with fresh ginger if you can; it makes a bigger difference here than almost any other ingredient swap.
- Strain into fresh ice, not the ice used for shaking, so the float sits cleanly on top instead of clouding into melted shaker ice.
- Express the citrus peel by pinching it, skin-side down, over the drink before dropping it in — this releases aromatic oils across the surface.
Rescue this drink
- Not smoky enough
- Float a little more Islay Scotch, and pour it slowly so it stays on the surface rather than mixing through.
- Too sweet
- Reduce the honey syrup to 10ml.
- The float sinks instead of sitting on top
- Pour it more slowly, over the back of a spoon, onto fresh ice rather than directly into the liquid.
- You cannot smell itgeneral guidance
- Most of a drink's aroma is on top of it, not in it. Squeeze the peel skin-side-down over the surface before dropping it in — the oil should visibly spray. A twist placed in the glass without being expressed contributes almost nothing. Aroma also fades fastest of anything in a drink, so garnish at the moment of serving rather than in advance.
- Too stronggeneral guidance
- Stir or shake for a little longer to add dilution, or add a splash of chilled water. This is a spirit-forward drink by design, so some strength is expected.
- Too sourgeneral guidance
- Add a little more sweetener (simple syrup or the cocktail's usual sweetening ingredient), a small amount at a time.
- Served too warmgeneral guidance
- Chill the glass, ice and every ingredient ahead of time — a warm pour is the fastest way to lose a cold drink's balance. For one serving, there's no real fix beyond rebuilding it properly chilled; for a batch, keep everything refrigerated until the moment of serving and add ice last.
- Over-diluted (tastes watery)general guidance
- Likely shaken too long, or with too much ice surface area. For one serving there's no fixing it after the fact — rebuild with fewer, larger ice cubes and a shorter shake. Planning a batch? Shorten the ice-contact time across the whole round, not just this glass.
- Under-diluted (tastes harsh or too concentrated)general guidance
- For one serving, stir in a few drops of chilled water to open it up. For a batch, extend the shake time slightly on the next round.
- No cocktail shakergeneral guidance
- A secure jar or bottle with a tight-fitting lid, shaken firmly.
- No cocktail strainergeneral guidance
- A slotted kitchen spoon held across the shaker opening.
Make ahead & storage
Batch the base, finish at serving
Batch the 4 stable components days ahead and add fresh lemon juice when you pour.
Add about 27% water to the batch to replace what the ice would otherwise contribute, or it will pour noticeably harsher than a fresh one.
- Fresh lemon juice:
- Fresh citrus loses its aroma within hours and turns dull. Squeeze it on the day.
What it tastes like
The taste, and what drives it
off-dry, sharp, light — a sour-structured drink served over ice.
Off-dry
Dry → Sweet
Sweetened enough to take the edge off without reading as a sweet drink.
What drives it: Honey syrup — carries the most sugar into the glass.
Sharp
Soft → Sharp
Properly sharp. This is the axis the drink is built on.
What drives it: Fresh lemon juice — supplies the acidity.
Faintly bitter
Gentle → Bitter
A bitter edge you would only notice if you looked for it.
What drives it: Blended Scotch whisky — provides the bitterness.
Light
Light → Rich
Light-bodied. It refreshes rather than satisfies, which is usually the intention.
What drives it: Blended Scotch whisky — adds most of the weight.
Very bold
Delicate → Bold
Very bold — concentrated, and served small for that reason.
What drives it: Blended Scotch whisky — is the most concentrated thing in the glass.
What you smell first
- Citrus peelLeadsBefore the first sip
From Fresh lemon juice, Lemon peel
- Smoke
From Blended Scotch whisky, Islay Scotch whisky
- Oak
From Blended Scotch whisky, Islay Scotch whisky
- Floral
From Honey syrup
- Ginger
From Ginger syrup
Aromas marked as sitting above the drink reach you before the first sip — skipping that garnish changes the drink more than its size suggests.
How it was worked out
Each reading comes from the recipe's own recorded taste scores combined with what each ingredient contributes, weighted by how much of it is in the glass. Almost everything in this drink has detailed ingredient data behind it.
How balance actually works →If it isn't right
What goes wrong with this drink, and why
Only the faults this particular recipe is actually prone to — each with the likely cause, the adjustment, and what the adjustment costs you.
It's too sweet
- Likely cause
- Honey syrup is carrying the sugar here, and it is the easiest thing in the drink to over-pour — syrup clings to a jigger and a "splash" is rarely the same twice.
- What to change
- Cut honey syrup by about a third and rebuild. If it is already made, a squeeze of citrus is faster than starting again.
- What that does
- The drink will read sharper as well as less sweet, because the acid stops being balanced. That is usually the intention, but it is a bigger change than it sounds.
It's too sour
- Likely cause
- Fresh lemon juice varies more than any other ingredient in the drink. Limes differ by weeks of ripeness, and a sharp one can be half again as acidic as a mild one at the same measure.
- What to change
- Add sweetener a few millilitres at a time rather than diluting — you are correcting a ratio, not a concentration.
- What that does
- Sourness recedes and the drink gains a little weight. Overshoot and you will be reading the too-sweet entry above instead.
It's too strong
- Likely cause
- Blended Scotch whisky dominates by design here — this is a drink built to be sipped, and it is under-diluted more often than it is over-poured.
- What to change
- Shaking for longer, or add a measured 5–10ml of water. Both are the same correction; one is just more honest about it.
- What that does
- Alcohol heat drops and the aromatics open up — a slightly diluted spirit-forward drink usually smells better, not worse.
It's watery
- Likely cause
- Shaking adds water while it chills, and the two cannot be separated. Wet ice from a freezer door, or small cubes, will over-dilute before the drink is properly cold.
- What to change
- Use bigger, drier, colder ice and stop sooner. Chilling the glass first buys you time you would otherwise spend diluting.
- What that does
- More flavour concentration at the same temperature. Under-dilute instead and the drink will taste harsh — this is a target, not a direction.
It doesn't smell of anything
- Likely cause
- The aroma you are missing is probably citrus peel, which sits above the drink rather than in it — skipping or under-expressing the garnish removes it entirely.
- What to change
- Express the peel over the surface with the skin facing the drink, then drop it in. Herbs go in the glass, not on the side.
- What that does
- Aroma arrives before flavour does, so the whole drink reads as more intense without a single measure changing. The oil does land in the drink, though — an over-expressed peel adds a faint bitterness to the first mouthful.
Taste profile
- Sweetness
- 2/5
- Sourness
- 3/5
- Bitterness
- 1/5
- Strength
- 4/5
- Fruitiness
- 0/5
- Freshness
- 1/5
- Creaminess
- 0/5
- Smokiness
- 4/5
Nutrition & alcohol
Estimate onlyBased on standard pours at typical bottle strengths; brands and homemade syrup strengths vary.- Calories
- 190 kcal
- Sugar
- 14 g
- Carbohydrates
- 15 g
- Alcohol units (UK)
- 2.7
- US standard drinks
- 1.54
- ABV
- 22.8%
- Serving size
- 120 ml
Show calculation assumptions
Source: Calculated from standard measures
Calorie breakdown: ~151 kcal from alcohol, ~39 kcal from sugar and mixers.
Likely range: 143–238 kcal, reflecting the confidence level above — not a lab-measured figure.
Assumes 50ml blended Scotch at 40% ABV and an 8ml Islay Scotch float at 43% ABV.
These figures are estimates, not laboratory measurements — individual tolerance to alcohol varies. See our responsible drinking guidance.
Variations
Extra Smoky Penicillin
Increase the Islay Scotch float to 12–15ml for a more assertively peaty finish.
What kind of drink this is
The structure behind the recipe
A shaken build: a sour-structured whisky-based drink, served over ice — light and lively in the mouth.
Sour-structured
Something sour and something sweet held in balance over a base — the structure behind the whole sour family and everything descended from it.
Base
Blended Scotch whisky
Spirit in the largest measure — read as the base.
Modifier
Islay Scotch whisky
A spirit, but not the largest measure — read as a modifier.
Sour element
Fresh lemon juice
A short, sharp measure — recorded acidity 5/5, and nothing sharper is poured short, so this is the sour element.
Sweet element
Honey syrup
A syrup — its whole job in the drink is to sweeten and to add a little body along with it.
Ginger syrup
A syrup — its whole job in the drink is to sweeten and to add a little body along with it.
Drinks built this way are collected as the Sour family.
5 components' roles areworked out from the ingredient's category and recorded taste attributes rather than set by hand — the reasoning is shown above so you can disagree with it.
Technique
shaken
Ice is thrown against the liquid and against itself, chipping fragments off and driving air through the mix. Chilling, dilution and aeration all happen at once and cannot be separated.
A lighter, briefly frothy body and a cloudy appearance that settles as it stands. The aeration blunts alcoholic heat, which is why a shaken drink tastes softer than a stirred one of the same strength.
What it ruins: Clarity, and any carbonation. A shaken spirits-only drink arrives cloudy with ice shards floating in it, and shaking anything fizzy is the one rule with no exceptions.
Also involves layering.
Everything about shaking →How the technique works →Dilution
During mixing, then strained
Water from ice typically makes up around 30% of the finished drink for a shaken build (commonly 25–35%). Dilution is an ingredient here, not a side effect.
Why dilution is an ingredient →Served
Over ice
Rocks glass · 120ml
Served on ice, so it keeps chilling in the glass. A larger, colder, slower drink than the same spirits served straight up.
Texture and aroma
Shaking whips air through the drink, giving a lighter, briefly frothy body that settles as it stands.
Aroma arrives before flavour does. A citrus twist is expressed over the surface so its oils sit on top of the drink — skipping it changes the drink more than its size suggests.
Where to go from here
Each of these is here because of something specific about this drink, not as a standard set of links.
Drinking this with food: seafood, oysters and anything raw
On its recorded taste scores this drink meets the test for seafood, oysters and anything raw — the page explains the principle behind it rather than simply asserting the pairing.
Bar techniques worth the trouble
This one asks for real technique. The advanced path covers the methods behind it and is honest about which are worth the trouble.
Where it comes from
Origin and family
Origin of the Penicillin
Modern classic created in 2005 by Sam Ross at Milk & Honey, New York.
Family
Sour2 parts spirit · 1 part citrus · 1 part sweetener — shaken, strained, served up or over ice.
On drinks history
Cocktail origin stories are frequently repeated and rarely evidenced. Our history section separates what is documented from what is folklore rather than picking whichever version reads best.
History and culture →Try this next
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Use up your ingredients
Bought a bottle just for this? Here's what else it's good for.
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Recipe confidence
A well-documented modern classic with a widely agreed recipe and technique.